Coeliac disease in the oral mucosa?

Coeliac disease in the oral mucosa?

Response of the jejunal mucosa in adult coeliac disease to oral prednisolone.

Five patients with adult coeliac disease were treated with prednisolone for four to five weeks while continuing a normal gluten-containing diet. A prompt histological, ultrastructural and enzymic recovery of the jejunal mucosa in all five was accompanied by an incomplete metabolic response in three of four patients tested. These findings are discussed in relation to the possible immunological p...

autoimmune enteropathy: not all flat mucosa mean coeliac disease

a 62-year-old woman complaining of severe malabsorption was diagnosed with celiac disease based on the findings of flat, small intestinal mucosa and hla-dq2 positivity, although celiac serology was negative. this diagnosis was questioned due to the lack of clinical and histological improvement after a long period of strict gluten-free diet. the detection of enterocyte autoantibodies guided to t...

Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease Running head: TSLP in coeliac disease

From: First Department of Internal Medicine and Department of Molecular Medicine, St Matteo Hospital, University of Pavia, Pavia, Italy; Centre for Immunobiology, Barts and the London School of Medicine and Dentistry, London, UK; Department of Experimental Oncology, European Institute of Oncology, Milan, Italy; Faculty of Medicine, University of Southampton, Southampton, UK; Department of Gastr...

COELIAC DISEASE Regulation of the T helper cell type 1 transcription factor T-bet in coeliac disease mucosa

Background: In coeliac disease (CD) mucosa, the histological lesion is associated with marked infiltration of T helper cell type 1 (Th1) cells. However, the molecular mechanisms which regulate Th1 cell differentiation in CD mucosa are unknown. Aims: To analyse expression of transcription factors which control the Th1 cell commitment in CD. Patients: Duodenal mucosal samples were taken from untr...